Psoriasis — a chronic, non-communicable disease, skin conditions, reaching out especially to the skin. Usually psoriasis causes the education of excessively dry, red, elevated, on the surface of the skin in patches. However, in some patients, the psoriasis, you do not have any sign of damage to the skin.
The degree of severity of the disease may vary in different patients, and even in the same patient, during the periods of remission and flare-in a very wide range, from small local lesions, for a total of up to cover the entire body psoriatic plaques. Many times, there is a tendency to progression of the disease over time (especially when they are in the absence of the treatment), to make, and the awakening of the exacerbation, the increase of the square of the failure and the commitment to new areas of the skin. Some patients may experience a continuous stream, as a disease of spontaneous remission, or even a continuous progression. Many times, they are taken by surprise by the nails in the hands and/or feet (psoriatic onihodistrofiya). With the defeat of nails you can be isolated, observed, that in the absence of skin lesions. Psoriasis can also cause inflammation the defeat of the joints, called psoriatic arthropathy or psoriatic arthritis. A 10% to 15% of patients with psoriasis also suffer psoriatic arthritis.
There are a wide variety of tools and methods for the treatment of psoriasis, but due to the chronic, recurrent nature of the disease itself, and a lot of the times, according to the trend of development in the course of time, the psoriasis is a very difficult to treat the disease. A complete cure is not possible at this time (that is, a psoriasis, which is incurable when the current level of development of medical science), but there may be more-or-less-long, more-or-less complete remission, including a one-time purchase). However, it always remains the risk of a relapse.
The causes of psoriasis
- Stress, depression,
- A skin infection, especially by viruses, by bacteria such as staphylococci. the streptococcus), fungi (Candida);
- Hereditary predisposition;
- The disease, which affects the regeneration of the skin cells;
- A failure in the functioning of the endocrine system (hormonal disorders)
- Diseases of the digestive system enteritis, ulcerative colitis, dysbacterioses (dysbiosis);
- Disease of the liver.
More details about the cause of psoriasis
The impaired barrier function of the skin as possible, and in particular, to a mechanical release or by irritation, friction, and pressure on the skin, the overuse of soap and cleaning supplies-chemicals contact with solvents, household cleaning products, alcohol, mud, to the existence in infected lesions of the skin or allergy of the skin, and excessive dryness of the skin will also play a key role in the development of psoriasis.
Psoriasis is a large part of idiosyncratic disease of the skin. The experience of the majority of the patients, and he says that psoriasis can be as a matter of course, in order to improve, or worsen, for no apparent reason. A study of the various factors that are associated with the occurrence of, development of, or worsening of psoriasis they tend to be based on the study of tiny, usually a hospital (not the clinic), that is to say, considerably heavier, and the groups of the patients of psoriasis. Thus, these studies tend to suffer from a lack of coverage of the sample size and the inability to identify a causal relationship in the presence of a large number of other (including as yet unknown or unidentified) factors that may affect the nature of the flow of psoriasis. In many cases, different studies have detected conflicting findings. However, the first signs of psoriasis often appear when you are suffering from stress (physical or mental), injury of the skin on the areas of the first appearance of psoriatic rash and/or migrated by streptococcal infections. The conditions, according to several sources, and this may have contributed to the deterioration and decay of the current in the psoriasis includes acute and chronic infection, stress, weather changes, and the changing of the seasons. Some of the drugs, according to a number of sources that are associated with the decay of the current in the psoriasis or it can lead to the main event. The over-consumption of alcohol, smoking, being overweight or obese, a poor diet can make it more heavy duty for the psoriasis and make it difficult for the treatment for the cause of the problems. The lacquer for the hair, some face creams and hand lotions, cosmetics, perfumes, and chemicals can also result in the worsening of psoriasis in some patients.
Psoriasis is more commonly developed in patients with an initially dry, thin, sensitive skin in patients with oily or well-moisturized skin, and it is far more common in women than in men. You have a patient with psoriasis most commonly appears for the first time, in areas of very dry or thin skin in areas of skin, oily skin, and, in particular, often appears in the places of the damage to the health of the skin and the integument, including scratching, scuffing, abrasions, scratches, cuts, and in areas that are exposed to friction, pressure, or contact with harsh chemicals, detergents and solvents. It is supposed that this phenomenon in lesions of psoriasis, first of all, the dry, flat or wound on the skin that is associated with the infection is the fact that infecting the body, it penetrates easily into the skin, and with the least amount of secretion of sebum, which in other conditions and protects the skin from infections), or in the event of damage to the skin. The most favorable conditions for the development of psoriasis, and therefore, to the contrary, the most favourable conditions for the development of a fungal infection is stopped (a so-called "athlete's foot") or in the armpit, in the groin area. For the development of fungal infections, the more favorable the wet, wet to the skin, for psoriasis, and vice-versa in dry season. He slid it in to the skin, the infection causes a dry (non-exudative) is a chronic inflammation, which, in turn, causes the symptoms typical for psoriasis, such as itching, and an increase in the proliferation of the cells of the skin. This, in turn, leads to a further increase of the dryness of the skin, as a result of inflammation, and increased proliferation of keratinocytes, and due to the fact that the infecting your body uses up the moisture, which otherwise would be used to hydrate the skin.
The symptoms of psoriasis
- Severe itching of the skin;
- The appearance of the skin, a small rash, and that as far as the development of on the net reveal it, are the shell, the more connected to those in uniform, in inflammatory areas, which are covered in a gray-and-white, sometimes with a yellow ring (with t. n. psoriat- diffraction label);
- The bleeding of the plates;
- Psoriasis of the nails the first havetalmaet, and then receivet, and the nail is not provided;
- It is possible pain in the joints.
The degree of severity of the psoriasis phase psoriasis)
Psoriasis is usually graded according to the degree of gravity.
- Psoriasis grade 1 (level easy to do with the defeat of not more than 3% of the surface area of the skin);
- Psoriasis, 2nd grade (with an average severity of loss of 3% to 10% of the surface area of the skin);
- Psoriasis grade 3 (heavy duty) with the participation of more than 10% of the surface area of the skin.
Psoriatic the defeat of the joints, is considered to be a severe form of psoriasis, regardless of whether the square of the lesions of the skin.
Types of psoriasis
Psoriasis can manifest itself in many ways. Options for psoriasis include common, simple (ordinary), or, otherwise, the plaque psoriasis (psoriasis vulgaris, plaque psoriasis), пhavewiththaveлезnth psoriasis (pustular psoriasis), drop-by-drop, on the way to or from psoriasis (guttate psoriasis), psoriasis, bendtsprucens surfaces (flexural psoriasis). The following is a brief description of each of the assortment of the psoriasis, in conjunction with the code of the International classification of diseases (ICD-10).
Plaque psoriasis, or for ordinary psoriasis, psoriasis vulgaris, simple psoriasis (psoriasis vulgaris) is the most common form of psoriasis. It is seen in 80% to 90% of all psoriasis patients. Plaque psoriasis vulgaris most of the time manifests itself in the form of a typical elevated above the surface of the skin is healthy, the portions inflamed, red, hot skin, covered with a grey or white, off-white, easy-to-ontlivaudais, scaly, dry and thickened skin. Red leather underneath, easily removed, gray, or white layer, easy-to-tRAвмandрhaveеtXia and it hurt, because it contains a large number of small vessels. These patches of typical injury and psoriatic arthritis is called psoriatic plaques. Пwithonрandаt- diffraction plaque have a tendency to increase in size, merging with the adjacent plate, forming a whole card, name tag ("the wax lake").
Psoriasis bendtsprucens surfaces (flexural psoriasis), or of "psoriasis, inverse" (inverse psoriasis) usually looks good, it's not flaky, or with the least amount of hull, it is not especially protruding above the surface of the skin is red, inflamed blemishes, and it was established only in the folds of the skin, and in the absence of or a minimal defeat, in other parts of the skin. Most often, this form of psoriasis affects the folds in the area of the genitals, the groins, the inner thighs, the armpits, the folds up under the increased in obese belly (psoriatic pannus and skin folds under the milk by the glands of the female. This is a form of psoriasis that is particularly vulnerable to deterioration under the influence of the friction and injuries of the skin, and the allocation of sweat, and it is often accompanied by, or complicated with secondary fungal infection, or withtraptonкonккonвonй pyoderma.
The guttate psoriasis (guttate psoriasis) is characterized by the presence of a large number of small, high-up on the surface of the skin is healthy, dry, red, and purple (the color purple), similar to the shape of a tear drop, or a small dot, and the circle of items to destroy. This psoriat- diffraction elements that often cover large areas of the skin, most commonly on the hips, but it can also be seen on the legs, arms, shoulders, scalp, back of the neck. Guttate psoriasis, often for the first time, we develop or worsen after a streptococcal infections, in ordinary cases, after withtraptonкonккonвonй the pain of angina or a withtraptonкonккonвongon pharyngitis.
Пhavewiththaveлезnth psoriasis or экwithwithhaveдаtYvesnth the psoriasis is more severe skin forms of psoriasis, and it seems that it rose above the surface of the skin blisters or bullae, filled with uninfected, transparent inflammatory экwithwithhaveдаtonм (pustules). The skin above and below the surface of пhavewiththaveл, and all around them the red, hot, ontechnth, вonwithпалеnnth and havetonлщеnnth, easy-to-exfoliate. It can occur in secondary infections and пhavewiththaveл, in this case, the exudate acquires a purulent nature. Пhavewiththaveлезnth psoriasis can be limited, localized, with the most common location is the cards from the ends of the extremities (hands and feet), that is to say, in the legs and arms, this is called palmoplantaris пhavewiththaveлез (palmo-plantar pustulosis). On the other, in the most severe cases of пhavewiththaveлезnth psoriasis can be GEnеRAлandзonваnnth, with the wide spread of the пhavewiththaveл on the whole surface of the body, and the tendency towards the merging of large pustules.
Psoriasis of the nails, or psoriatandчеwithкth onihodistrofiya leads to a variety of changes in the appearance of the nails, on the fingers, hands, or feet. These changes can include any or a combination of the change in the color of the nail and the nail bed (yellowing, appearance, and white), the look and feel of your nails, and the nails, dots, spots, cross-sectional, andwithчерчеnnonwithtand nails, lines, and thickening of the skin underneath the nails of the hands and around the nail bed, de-lamination and thickening of the nails, the total loss of the nail (onnandхonлandзandwith), and the development of increased fragility of the nails.
Psoriatic arthritis, or psoriatandчеwithкth arthropathy, arthropathic psoriasis and is accompanied by inflammation of the joints and connective tissue. Psoriatic arthritis can affect any joint, but most often the small joints of the distal falang the fingers of the hands and/or feet. This is the typical case, by causing swelling of the fingers, hands, and feet, also known as psoriatic dactylitis. Psoriatic arthritis can also hurt tазonбедреnns, the joints of the knee, плechелonпаtonчnth the articulation, the joints, the bones of the spine (ankylosing psoriatic arthritis). At times, psoriatic arthritis, arthritis of the knee or hip joints and, in particular, for spondylitis psoriatic arthritis is so severe, that it leads to a severe impairment, the patient's inability to travel without special arrangements. The fatality when more severe forms of psoriatic arthritis, boosts, as well as the detention of the patient in the bed also contributes to the occurrence of pressure ulcers, and pneumonia. About 10 to 15 percent of psoriasis patients also suffer psoriatic arthritis.
Пwithonрandаtandчеwithкth эрandtрonдермandя, or erythrodermic psoriasis, manifesting itself in common, a lot of times GEnеRAлandзonваnnth inflammation and the skin, ontwithлonйкonй of the skin, either in whole or in large part, to the surface of the skin. Пwithonрandаtandчеwithкth эрandtрonдермandя may be subject to intense skin problem, itching, swelling of the skin and of the subcutaneous tissue also contributes to the pain of the skin. Пwithonрandаtandчеwithкth эрandtрonдермandя it is often the result of a worsening of psoriasis vulgaris, when the unstable, long, and especially when it's a sudden cut to the abolition of the system of treatment, or to local glucocorticoids. It can also occur as a result of the provocation of alcohol, neuro-mental stress, andntеркhaveрреntnthand infections (particularly colds, iran). This form of psoriasis can also be deadly, because it is extremely strong, the inflammation and sloughing, or the separation of the skin and damage the body's ability to regulate the temperature of the body, and barriernhaveю the function of the skin, which can be a complicated and generalized pyoderma or sepsis. However, it's limited, located in psoriatandчеwithкth эрandtрonдермandя you can be the first symptom of psoriasis, later on, tRAnwithфonрмandрhaveяwithь in the common plaque psoriasis.